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Table 8 Antidepressants, Antipsychotics and Gender Differences

From: Gender and race disparities in weight gain among offenders prescribed antidepressant and antipsychotic medications

  Women Men  
   95 % confidence interval   95 % confidence interval  
  Mean (SD) [Lower, Upper] Mean (SD) [Lower, Upper] p
Antidepressant n = 53 n = 271  
 Weight change (kg) 6.4 (11.2) [3.5, 10.0] 2.0 (9.7) [0.8, 3.3] 0.007
 Percent weight change 8.5 (15.7) [4.5, 13.6] 2.9 (10.6) [1.7, 4.4] 0.012
 BMI change 2.5 (4.4) [1.3, 3.9] 0.6 (3.0) [0.3, 1.1] 0.004
 Duration (years)† 2.1 (0.9) [1.8, 2.3] 2.4 (1.1) [2.2, 2.5] 0.055
Antipsychotic n = 16 n = 156  
 Weight change (kg) 8.8 (17.8) [−0.6, 18.3] 1.6 (11.8) [−0.3, 3.7] 0.122
 Percent weight change 13.9 (29.6) [−1.9, 29.6] 3.3 (13.8) [1.2, 5.8] 0.166
 BMI change 3.4 (7.2) [−0.4, 7.3] 0.5 (3.8) [−0.1, 1.1] 0.126
 Duration (years) 1.9 (1.0) [1.3, 2.4] 2.5 (1.0) [2.3, 2.7] 0.027
FGA n = 7 n = 92  
 Weight change (kg) 10.8 (17.2) [−5.1, 26.6] 0.9 (12.2) [−1.7, 3.7] 0.096
 Percent weight change 15.8 (31.4) [−13.3, 44.8] 2.7 (14.1) [−0.3, 6.0] 0.142
 BMI change 4.1 (7.2) [−2.5, 10.8] 0.3 (3.9) [−0.5, 1.2] 0.094
 Duration (years) 1.7 (1.0) [0.7, 2.6] 2.4 (1.1) [2.2, 2.6] 0.093
SGA n = 9 n = 64  
 Weight change (kg) 7.3 (19.2) [−7.4, 22.1] 2.5 (11.1) [−0.2, 5.6] 0.568
 Percent weight change 12.4 (29.8) [−10.5, 35.3] 4.1 (13.3) [0.8, 7.8] 0.633
 BMI change 2.9 (7.6) [−3.0, 8.8] 0.8 (3.5) [−0.1, 1.7] 0.609
 Duration (years) 2 (1.1) [1.2, 2.8] 2.7 (1.0) [2.4, 2.9] 0.100
  1. Length of time between baseline and last observed weight